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- Presentation
Vaccination Recommendations for Adults Receiving Biologics and Oral Therapies
Description
The presentation covers vaccination recommendations for adults receiving biologics and oral therapies, particularly focusing on those with conditions such as psoriasis and psoriatic arthritis. The speaker discusses general vaccination guidelines for adults, highlighting specific vaccines, age groups, and considerations for immunocompromised individuals. It details vaccines like COVID-19, influenza, RSV, Tdap, MMR, varicella, shingles, HPV, pneumococcal, and hepatitis, with distinctions made between live and non-live vaccines. Key recommendations are outlined for patients on immunomodulatory treatments, emphasizing the importance of determining necessity, efficacy, and safety of vaccinations in the context of their therapies. Non-live vaccines can generally be administered without modification, while live vaccines require a pause in most therapies before and after administration. Specific adjustments for medications such as methotrexate and biologics are discussed, providing insights into optimal timing for vaccinations relative to drug administration. The Delphi consensus process involved in developing these guidelines is also noted, emphasizing the need for personalized decision-making based on individual patient factors and treatment contexts.
View moreConclusions
- Non-live vaccines do not generally require alterations to existing therapies.
- Live vaccines typically necessitate a pause in most therapies before and after vaccination.
- Apremilast and acitretin can continue with live vaccines without interruption.
- Methotrexate therapy may require interruption when administering non-live and live vaccines.
- Recommendations regarding vaccine administration depend on medication half-lives and viremia duration of the vaccines.
- Decisions about vaccination should be individualized based on patient-specific factors.
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