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  • Presentation

Treatment of Central Centrifugal Cicatricial Alopecia

Description

Dr. Amy McMichael presented on Central Centrifugal Cicatricial Alopecia (CCCA), a common hair disorder particularly affecting women of African descent, often presenting with various symptoms and significant clinical severity. The condition typically arises before age 60, with associations linked to hair tension styles and a potential genetic predisposition, although causal relationships remain unclear. Research indicates a possible genetic variant present in a significant percentage of patients, but a comprehensive understanding of underlying genetics is still needed. The presentation emphasized the necessity for thorough evaluations, including dermatoscopic examinations and biopsies, to determine the appropriate treatments for CCCA patients. Treatment strategies include managing inflammation, using topical and systemic medications like minoxidil and steroids, and addressing tractional stresses on the scalp. The talk highlighted the importance of long-term maintenance of treatment, as discontinuation can lead to worsening conditions. Dr. McMichael also discussed recent approaches involving low-level laser therapy and platelet-rich plasma (PRP), underscoring the necessity for ongoing patient education and engagement. A patient resource page was made available to assist in their understanding of CCCA and to promote better management of the condition.

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Conclusions

  • CCCA predominantly affects women of African descent between the ages of 30 to 65.
  • There is a need for better understanding of genetic and environmental factors contributing to CCCA.
  • Various hair styling practices, such as extensions and braids, are associated with CCCA but not necessarily causal.
  • Clinically, CCCA presents with a range of symptoms, from mild to severe, often leading to significant discomfort prior to diagnosis.
  • The disease may have an autosomal dominant genetic pattern, indicated by family histories of CCCA.
  • Trichoscopy is a critical diagnostic tool that can help in evaluating disease severity and treatment response.
  • A multi-faceted treatment approach, incorporating corticosteroids, antibiotics, and hair restoration techniques, is recommended for CCCA.
  • Adherence to treatment is crucial, as discontinuation can lead to a return or worsening of symptoms.
  • Emerging therapies, including PRP and metformin, show promise in improving symptoms of CCCA.
  • Long-term management and education about the chronic nature of CCCA are essential for patient care.
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