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- Presentation
Top Contact Allergens in Children
Description
Doctor Margo Reader discusses the prevalence of allergic contact dermatitis in children, emphasizing the importance and safety of patch testing, which is often underutilized for this age group. Children can develop contact dermatitis similarly to adults, yet referrals for testing are significantly lower for kids. The talk highlights the most common allergens identified through study data, with nickel being the most prevalent, followed by other allergens like thimerosal, cobalt, fragrances, and methyl isothiazolinone (MI). The presentation underscores that children have unique exposure sources, including toys, personal care products, and household items, leading to potential allergic reactions. Reader stresses the need for comprehensive patient history, taking into account children's special circumstances such as daycare, hygiene products, and hobbies. She illustrates how common allergens can be found in products marketed for children. Special attention is drawn to how even products labeled as hypoallergenic can still contain problematic ingredients and to the ongoing challenge of managing fragrance allergies due to labeling regulations. The talk concludes by reiterating the need to recognize various allergens and their relevance in children as well as advocating for more frequent patch testing in pediatric dermatology.
View moreConclusions
- Kids are frequently diagnosed with allergic contact dermatitis (ACD), and patch testing is safe and underutilized in this population.
- The prevalence of ACD in children is similar to that in adults, yet children are referred for patch testing less frequently.
- Top contact allergens in children include nickel, thimerosal, cobalt, and various fragrances, with nickel being the most common.
- Nickel allergy is more prevalent in girls and can originate from jewelry and toys, highlighting the need for regulation.
- Collecting a thorough history on children's exposures is crucial for effective diagnosis and treatment, as kids have different exposures than adults.
- Children's personal care products often contain allergenic preservatives like methylisothiazolinone and fragrances, raising concerns about their safety.
- Toys frequently contain allergens such as nickel, which can lead to sensitization and dermatitis in children.
- Patch testing should account for the unique exposure landscape of children, which includes daycare settings, personal care products, and common hobbies.
- Silverberg JI, Hou A, Warshaw EM, DeKoven JG, Maibach HI, Belsito DV, Zug KA, Taylor JS, Sasseville D, Dunnick CA, Houle MC, Atwater AR, Reeder MJ, DeLeo VA, Pratt MD, Fowler JF Jr, Zirwas MJ, Marks JG Jr. Age-related differences in patch testing results among children: Analysis of North American Contact Dermatitis Group Data, 2001-2018. J Am Acad Dermatol. 2022 Apr;86(4):818-826. doi: 10.1016/j.jaad.2021.07.030. Epub 2021 Jul 24. PMID: 34314743.
- Young K, Collis RW, Sheinbein D, Shope C, Suresh T, Tam I, Snyder A, Cotton C, Hunt R, Goldenberg A, Goldminz A, Lugo-Somolinos A, Grisham E, Martin KL, Sandhu M, Eichenfield DZ, Sprague J, Kleinman EP, Sum K, Chen JK, Teng J, Aquino MR, Plante J, Franca K, Onate A, Udrizar P, Liszewski W, Yu J. Pediatric Allergic Contact Dermatitis Registry patch testing results from 2016 to 2022: A retrospective study of age-related differences. J Am Acad Dermatol. 2023 May;88(5):1218-1220. doi: 10.1016/j.jaad
- Isufi D, Jensen MB, Kursawe Larsen C, Alinaghi F, Schwensen JFB, Johansen JD. Contact Dermatitis. 2025 Jan 19. doi: 10.1111/cod.14753. Epub ahead of print. PMID: 39827476.
- Bonchak JG, Prouty ME, de la Feld SF. Prevalence of Contact Allergens in Personal Care Products for Babies and Children. Dermatitis. 2018 Mar/Apr;29(2):81-84.
- Berk DR, Bayliss SJ. Cellular phone and cellular phone accessory dermatitis due to nickel allergy: report of five cases. Pediatr Dermatol. 2011 May-Jun;28(3):327-31. doi: 10.1111/j.1525-1470.2011.01313.x. Epub 2011 Mar 31. PMID: 21453303.
- Kullberg SA, Gupta R, Warshaw EM. Methylisothiazolinone in children's nail polish. Pediatr Dermatol. 2020 Jul;37(4):745-747. doi: 10.1111/pde.14147. Epub 2020 Mar 20. PMID: 32198778.
- Tran JM, Reeder MJ. When the treatment is the culprit: Prevalence of allergens in prescription topical steroids and immunomodulators. J Am Acad Dermatol. 2020 Jul;83(1):228-230.
- Botvid S, Simonsen AB, Jørgensen C, Müller S, Kirkeby CS, Christensen AB, Johansen JD. Fragrance allergens in cosmetic products marketed for children in Denmark. Contact Dermatitis. 2023 Nov;89(5):374-381. doi: 10.1111/cod.14397. Epub 2023 Aug 17. PMID: 37591237.