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  • Presentation

The Science of Cosmoseuticals and Nutraceuticals with a Focus on the Exposome

Description

The presentation discusses the science behind cosmoseuticals, nutraceuticals, and the concept of the exposome, which encompasses all exposures impacting the body throughout life. Distinguishing the exposome from exosomes, the speaker emphasizes its role in skin aging, identifying it as a critical factor beyond traditional views of intrinsic and extrinsic aging. The exposome includes influences from both environmental factors (like pollution and tobacco smoke) and internal factors (like diet and sleep), all of which contribute to oxidative stress via reactive oxygen species. Important components of this concept include the microbiome's role in aging and health and the impact of various dietary factors, including antioxidants and adaptogens, on skin health. The presentation advocates for a shift from anti-aging to regenerative dermatology, highlighting the need to maintain and restore skin health through cosmoseuticals that address UV and oxidative damage, and nutraceuticals that enhance internal defense mechanisms. Ultimately, a multidisciplinary approach considering the exposome is proposed for effective skin care and treatment.

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Conclusions

  • The exposome encompasses all internal and external exposures affecting the body from conception to death.
  • Skin aging is influenced by both intrinsic and extrinsic factors, with the exposome concept broadening the understanding of these influences beyond just sun exposure.
  • Reactive oxygen species (ROS) formation and destruction are central to age-related skin damage, affected by both cosmoseuticals and nutraceuticals.
  • Exogenous chemicals and stressors, including pollution and tobacco smoke, contribute significantly to skin aging through their impact on the exposome.
  • Maintaining a healthy microbiome is essential for both skin health and overall aging, as it is linked to dietary habits and systemic health.
  • Adequate sleep and stress management are vital for maintaining skin health and robust immune responses.
  • Utilizing adaptogens and antioxidants can help mitigate the effects of the exposome on skin aging.
  • Diet plays a critical role in modulating the exposome, with antioxidants such as vitamins C and E, polyphenols, and other nutrients being essential for skin health.
  • Cosmoseuticals can be effective in protecting the skin barrier from external insults, while nutraceuticals can improve internal antioxidant capacity.
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