Please login or create an account. If you do not have access to this content, you will be shown a 30 second preview and licensing options.

  • Presentation

The Metabolic Revolution: Nutrition Update for the Dermatologist

Description

The presentation by Katie Burruss, a dermatologist with a background in nutritional biochemistry, focuses on the relationship between nutrition and dermatology, particularly the obesity epidemic in the U.S. She discusses how the introduction of high fructose corn syrup in the 1970s contributed to rising obesity rates and outlines several factors such as increased reliance on ultra-processed foods, larger portion sizes, and socioeconomic barriers that hinder access to healthy foods. The talk emphasizes the impact of dietary choices on skin health, particularly conditions like acne and psoriasis, through mechanisms such as inflammation, insulin resistance, and gut dysbiosis. Burruss explains how high glycemic index foods can trigger systemic inflammation, worsen skin conditions, and contribute to premature aging by damaging collagen and elastin through glycation. She advocates for dietary modifications, suggesting a Mediterranean-style diet rich in whole foods, low in processed ingredients, and the inclusion of antioxidants to support skin and gut health. The key takeaway is that a balanced diet can improve not only overall health but also specific dermatological conditions, reinforcing the idea that diet plays a crucial role in skin health.

View more

Conclusions

  • The obesity epidemic in the United States has been linked to dietary changes, particularly the increase in ultra-processed foods and high fructose corn syrup.
  • High fructose corn syrup contributes to chronic inflammation and metabolic disorders, including insulin resistance and obesity.
  • High glycemic index diets trigger systemic inflammation, worsening dermatologic conditions such as acne and psoriasis.
  • Dietary modifications, such as adopting a low-glycemic, whole-food diet, can have a positive impact on skin health.
  • Maintaining a healthy gut microbiome is crucial for mitigating skin conditions related to obesity and dietary choices.
  • The consumption of colorful fruits and vegetables rich in antioxidants can combat oxidative stress, thereby supporting skin health.
  • Dietary practices play a significant role in skin aging and the development of conditions like psoriasis and acne.
  • Kunz, M.; Simon, J.C.; Saalbach, A. Psoriasis: Obesity and Fatty Acids. Front. Immunol. 2019, 10, 1807
  • Ogawa, K.; Stuart, P.E.; Tsoi, L.C.; Suzuki, K.; Nair, R.P.; Mochizuki, H.; Elder, J.T.; Okada, Y. A Transethnic Mendelian Randomization Study Identifies Causality of Obesity on Risk of Psoriasis. J. Investig. Dermatol. 2019, 139, 1397-1400
  • Hirt, P.A.; Castillo, D.E.; Yosipovitch, G.; Keri, J.E. Skin changes in the obese patient. J. Am. Acad. Dermatol. 2019, 81, 1037-1057
  • Meixiong, J.; Ricco, C.; Vasavda, C., et al. Diet and acne: A systemic review. JAAD Int. 2022 Mar 29;7:95-112.
  • Afvari, S.; Beck, T.; Kazlouskaya, M. et al. Diet, sleep and exercise in inflammatory skin diseases. Our Dermatol Online. 2023;14(4):430-435.
  • Semba, R.D.; Nicklett, E.J.; Ferrucci, L. Does accumulation of advanced glycation end products contribute to the aging phenotype? J Gerontol A Biol Sci Med Sci. 2010;65:963-75
  • Gkogkolou, P.; Bohm, M. Advanced glycation end products: Key players in skin aging? Dermatoendocrinol. 2012;4:259-70.
  • Diotallevi, F.; Campanati, A.; Martina, E.; Radi, G.; Paolinelli, M.; Marani, A., et al. The role of nutrition in immune-mediated, inflammatory skin disease: a narrative review. Nutrients. 2022;14:591.
  • Conforti, C.; et al. Acne and diet: a review. Int J Dermatol. 2022; Aug 6 (8):930-934.