Please login or create an account. If you do not have access to this content, you will be shown a 30 second preview and licensing options.

  • Presentation

The Eschar: Dermatological Emergencies

Description

Dr. Ted Rosen, a professor at Baylor, discusses the clinical significance and contextual understanding of eschars in dermatological emergencies. Using pattern recognition, he explains that an eschar, defined as a black, adherent crust on an ulcer, can indicate serious systemic issues, often related to infections or other medical conditions. Contextual factors like patient health, fever status, and lesion characteristics play vital roles in diagnosis and treatment. He presents various cases illustrating infections caused by specific pathogens, such as pseudomonas and mucormycosis, stressing the importance of history, including travel and exposure, in identifying potential causes. The presentation emphasizes the urgency of recognizing eschars and understanding their implications, highlighting the necessity for thorough patient assessment and timely intervention. Specific management strategies, including the use of antibiotics and the importance of biopsies at the site of the eschar are discussed, alongside the potential role of surgical intervention. Ultimately, Dr. Rosen underscores the need for an organized approach to evaluate patients with eschars and encourages healthcare professionals to be vigilant in their recognition and treatment.

View more

Conclusions

  • Eschar formation in dermatology may indicate a serious underlying systemic issue, often infectious in nature.
  • The clinical context, including patient history and presenting symptoms, is crucial for diagnosing the cause of skin eschars.
  • Common conditions associated with eschar formation include ecthyma gangrenosum, mucormycosis, cholesterol emboli, and calciphylaxis.
  • Patient health factors such as diabetes, immunocompromised status, and recent travel history significantly influence diagnosis and management.
  • Rapid developments of eschars warrant immediate attention, particularly in neutropenic or immunocompromised patients due to high mortality rates with certain pathogens like Pseudomonas.
  • Causative agents for eschar formation include various bacteria, fungi, and potential toxic exposures, demanding thorough investigation through patient history and appropriate laboratory tests.
  • In cases of severe necrotizing infections like mucormycosis, aggressive medical and surgical intervention is often necessary to prevent fatal outcomes.
  • Med Clin North Am 92:427-441, 2008
  • Cutis 90:67-69, 2012
  • An Bras Dermatol 92: 698-700, 2017
  • IDCases. 2023 Jan 13;31:e01694
  • Eur J Clin Microbiol Infect Dis. 2015;34:633-9
  • Case Rep Dermatol. 2024;16(1):240-247
  • Mycopathologia. 2016; 181(9): 759-763
  • Arch Dermatol Res. 2023;315(9):2717-2719
  • Crit Rev Microbiol 39:310, 2013
  • MMWR. 2021; 70:1750-1751
  • J. Fungi 2021; 7:298-304
  • Emerg Infect Dis. 2022-304 28:1-8
  • Am Fam Physician 76:539, 2007
  • Dan Med J. 2013;60(11):B4698
  • Swiss Med Weekly 2006;136:447-463
  • Ann Emerg Med 44:608, 2004
  • Toxicon 44:693, 2004
  • J Emerg Med 41:e31, 2011
  • YALE JOURNAL OF BIOLOGY AND MEDICINE 93 (2020), pp.1-xxx.