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  • Presentation

Syphilis Update 2024

Description

In the 2024 Syphilis Update, Dr. Aaron Amerson, Chief of Dermatology at San Francisco General Hospital, presents an overview of the rising syphilis rates in the U.S., emphasizing the need for increased awareness and education about the disease. The talk highlights recent epidemiological trends over the past decade, indicating significantly increased rates, especially among men who have sex with men and racial minorities, including alarming rises in congenital syphilis among Native Americans. Factors contributing to this resurgence include decreased public health efforts due to the COVID-19 pandemic and a shortage of the primary treatment, Bicillin LA. Amerson notes the importance of accurate and early diagnosis, as many cases go unrecognized until late stages. He urges healthcare providers to recognize atypical clinical presentations and to increase screening, particularly among high-risk groups. The discussion also covers the need for vaccinations, prompt treatment protocols, and the significance of addressing social determinants of health affecting syphilis transmission. The session underscores the complexities of managing syphilis effectively given the current epidemiological challenges and highlights the necessity of updated testing and treatment strategies.

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Conclusions

  • Syphilis rates are increasing in the U.S., particularly among women and Native American populations.
  • There are significant racial, ethnic, and sexual orientation disparities in syphilis rates.
  • Syphilis is often diagnosed late, indicating a need for improved recognition among healthcare providers.
  • The COVID-19 pandemic adversely affected the screening and treatment resources for STIs, contributing to the rise in syphilis cases.
  • The only FDA-approved drug for treating syphilis, Bicillin LA, is currently in shortage due to increased demand and supply issues.
  • Congenital syphilis cases are rising alarmingly, with a reported cases of 3,755 in 2022.
  • Neurosyphilis can occur at any stage of syphilis and requires specific treatment regimens, differing from standard syphilis treatment.
  • Regular and increased screening is necessary for high-risk populations, including MSM, HIV-positive individuals, and pregnant women.
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  • Tuddenham S, Amerson EH, Castillo Valladares HB, Leslie KS. Resurgence of Syphilis in the US-USPSTF Reaffirms Screening Guidelines. JAMA Dermatology. November 2022;158(11).
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