Skin Cancer Prevention and Management: Approaches and Strategies

The presentation by Anoki Jampasaria focuses on strategies for skin cancer prevention, particularly primary prevention and managing patients with pre-existing conditions. Key points include identifying patients at high risk for skin cancers, particularly those showing signs of field cancerization, characterized by extensive sun damage, and actinic keratoses. Various treatments are discussed, including topical therapies like fluorouracil, which has shown significant efficacy in preventing further skin cancers but may suffer from compliance issues due to patient discomfort. Alternative combination therapies, such as using fluorouracil with calcipotriene, have emerged to improve patient compliance while still delivering results. The importance of patient education regarding the treatment process, potential side effects, and follow-up is emphasized. Secondary prevention strategies involve chemoprevention methods such as nicotinamide and acetretin, particularly in immunocompromised patients, with the potential to significantly reduce new squamous cell carcinoma rates. The session also covered the use of oral capecitabine for patients with high disease burden or for those who do not respond to topical therapies. Ultimately, the presentation advocates for a comprehensive, tailored approach in managing skin cancer risk by incorporating innovative treatment strategies while ensuring patient support and adherence.