Please login or create an account. If you do not have access to this content, you will be shown a 30 second preview and licensing options.
- Presentation
Re-looking Erythema Migrans
Description
In this presentation about erythema migrans, Joe Pearson and faculty member Ankit Gore highlight the evolving understanding and clinical relevance of the condition associated with Lyme disease. They emphasize that the classic 'bull's eye' lesion is not commonly seen, as most erythema migrans lesions are oval-shaped and can mimic other skin issues, which makes diagnosis challenging. The discussion includes statistics on Lyme disease prevalence, with an estimated half a million cases in the U.S. annually, and stresses the importance of recognizing atypical presentations, especially in skin of color where symptoms may be missed or underreported. They address misdiagnosis issues linked to a heavy reliance on tick bite history and the necessity for awareness among healthcare providers, urging clinicians to base treatment on clinical findings rather than relying solely on patient history. Preventive measures against ticks, methods for identification, and the significance of treating erythema migrans appropriately, based on established guidelines, are also discussed. Additionally, they touch upon recent advancements in Lyme vaccine research and ongoing clinical trials that may enhance prevention strategies in the near future. The session aims to reeducate and equip healthcare professionals with a more nuanced understanding of erythema migrans for improved patient outcomes.
View moreConclusions
- Most erythema migrans lesions do not display the classic bull's-eye appearance.
- Erythema migrans occurs in about 80% of Lyme disease cases.
- Typical erythema migrans lesions are often oval and follow skin tension lines.
- A significant proportion of erythema migrans patients might not remember a tick bite, leading to missed diagnoses.
- There are various atypical presentations of erythema migrans, including multiple lesions that can present in a 'Christmas tree' pattern.
- Disparities exist in the diagnosis and treatment of Lyme disease based on skin color, with black patients more likely to have delayed diagnoses and more severe symptoms.
- Vesicular or bullous forms of erythema migrans are uncommon but documentable variations.
- Treatment guidelines for erythema migrans are consistent for solitary and multiple lesions, emphasizing clinical diagnosis over extensive testing.
- New Lyme disease vaccine trials are underway targeting various species of Borrelia, with potential availability in the near future.
- Kugeler KJ, et al. "By using commercial insurance claims data, we estimated that Lyme disease was diagnosed and treated is =476,000 patients in the United States annually." Emerg Infect Dis. 2021;27(2):616.
- Melski JW. "Language, logic, and Lyme disease." Arch Dermatol. 1999 Nov;135(11):1398-400.
- Brem CE, Goldberg LJ. "Early Erythema Migrans: Do Not Count on Plasma Cells." Am J Dermatopathol. 2022 Feb 1;44(2):e23-e25.
- Goldberg NS, Forseter G, Nadelman RB, Schwartz I, Jorde U, McKenna D, Holmgren D, Bittker S, Montecalvo M, Wormser GP. "Vesicular erythema migrans." Int J Dermatol. 2016 Feb;55(2):e79-82.
- Tiger JB, Guill MA 3rd, Chapman MS. "Bullous Lyme disease." J Am Acad Dermatol. 2014 Oct;71(4):e133-4.
- Paul S, Song PI, Ogbechie OA, Sugai DY, Morley KW, Schalock PC, Kroshinsky D. "Vesiculobullous and hemorrhagic erythema migrans: uncommon variants of a common disease." Int J Dermatol. 2016 Feb;55(2):e79-82.
- Zhang ZZ, Hashemi DA, Kroshinsky D. "Disseminated Lyme disease with a herpetiform center." JAAD Case Rep. 2022 Mar 12;29:46-47.
- Doughty H, O'Hern K, Barton DT, Carter JB. "Vesiculobullous Lyme disease: A case series." JAAD Case Rep. 2022 Mar 12;29:46-47.
- Abrahams C, Brooks BE, Singer H, Robinson-Bostom L, Kawaoka J. "Vesicular Erythema Migrans with Subsequent Jarisch-Herxheimer Reaction Mimicking Cellulitis." Cureus. 2021;13(11):e19195.
- J Gen Intern Med. 2022 Aug;37(10):2597-2600.