Please login or create an account. If you do not have access to this content, you will be shown a 30 second preview and licensing options.

  • Presentation

Radiation Treatment for Dermatologic Disease

Description

In a comprehensive session led by Beth McClellan, Chief of Dermatology at Montefiore Einstein, experts discussed the role of radiation treatment in managing dermatologic diseases, particularly skin cancers and hypertrophic scars. Dr. KR Mehta, a specialist in radiation oncology, highlighted the fundamental principles of radiation, focusing on its electromagnetic spectrum and effects at the atomic level, especially DNA damage. The session covered the evolution of radiation treatments, including the transition from orthovoltage to megavoltage techniques, emphasizing the efficacy of radiation as an adjuvant therapy to surgery for skin cancers, particularly in cases of perineural invasion and positive lymph nodes. Attendees learned about the benefits of radiation not only for malignancies but also for benign conditions like hypertrophic scars. Various radiation modalities were explained, including brachytherapy, superficial X-ray treatments, and the use of different delivery techniques. The discussion also touched on dose management strategies, the balance between tumor control and normal tissue preservation, and the potential side effects of radiation therapy, such as dermatitis. Overall, the session aimed to enhance understanding of radiation's clinical applications and safety considerations for dermatologic treatments.

View more

Conclusions

  • Radiation therapy can provide effective treatment for skin conditions including non-melanoma skin cancers.
  • Radiation can be an alternative for patients who are not suitable candidates for surgery due to comorbidities or tumor location.
  • Treatment outcomes such as local recurrence rates are comparable between radiation and surgical excision for basal and squamous cell carcinoma.
  • High dosage of radiation can lead to better control of tumors but may also result in poorer cosmetic outcomes.
  • Optimizing radiation techniques, such as hypofractionation, can improve patient tolerance and treatment results.
  • Advancements in radiation technology allow for more precise targeting of tumors, minimizing damage to surrounding healthy tissues.
  • Perineural invasion in squamous cell carcinoma increases complexity in treatment planning and may necessitate comprehensive radiation coverage.
  • Skin cancers, particularly of the head and neck area, benefit from tailored radiation therapy to enhance local control and cosmetic appearance.
  • https://doi.org/10.1038/s41392-020-0150-x
  • https://doi.org/10.3389/fphar.2019.00851
  • JAMA Otolaryngol Head Neck Surg. 2019;145(2):153-158. doi:10.1001/jamaoto.2018.3650
  • Int J Radiation Oncol Biol Phys, Vol. 103, No. 5, pp. 1109-1124, 2019
  • Cancer 2019;125:3582-3594.
  • Radiother Oncol. 2017 October : 125(1): 13-20. doi:10.1016/j.radonc.2017.08.011.