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  • Presentation

Photodermatoses in Skin of Color: Clinical Considerations, Presentation, and Management

Description

The talk reviewed photodermatoses in skin of color, emphasizing that erythema may appear violaceous, brown, or even as hyperpigmentation rather than bright red, which can make diagnosis and photo-testing more difficult. The speaker highlighted common and distinctive patterns in skin of color for polymorphous light eruption, chronic actinic dermatitis, actinic prurigo, drug-induced photosensitivity, lupus, lichen planus variants, erythropoietic protoporphyria, and xeroderma pigmentosum, noting differences in prevalence, morphology, and distribution across populations. Management themes included careful history-taking, phototesting and patch testing when contact/photoallergic dermatitis is suspected, photoprotection with attention to cosmetic acceptability, and treatment with topical steroids, calcineurin inhibitors, systemic immunosuppressants, dupilumab, and JAK inhibitors in more severe cases. A major focus was post-inflammatory pigment alteration, which can be more distressing and persistent than the primary rash and may take years to improve. The speaker also discussed sunscreen barriers in skin of color, recommending mineral or tinted sunscreens, shade matching, and secondary photoprotection options such as polypodium leucotomos extract.

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Conclusions

  • Photodermatoses occur across all skin types, but their prevalence and clinical appearance can differ substantially in skin of color.
  • Erythema is often harder to recognize in darker skin, so symptom history and careful exam are critical for diagnosis.
  • PMLE is common in skin of color and may present with more papular, neck-predominant, or easily misdiagnosed variants.
  • Chronic actinic dermatitis in skin of color is often more pigmentary, lichenified, and potentially widespread, making patch and phototesting especially important.
  • Actinic prurigo is disproportionately seen in Native American and Native Alaskan populations and can involve mucosal and ocular sites.
  • Drug-induced photosensitivity, including diltiazem-related eruptions, should be considered when new photodistributed hyperpigmentation appears in skin of color.
  • Photoaggravated disorders such as lupus and lichen planus can look different in skin of color and may present with more pigmentary change than classic erythema.
  • Genodermatoses with photosensitivity can occur in non-White populations, and consanguinity may increase risk in some groups.
  • Post-inflammatory pigment alteration is a major and often more distressing outcome than the primary rash for many patients with skin of color.
  • Treating the underlying inflammation quickly is important because pigmentary sequelae can persist for years.
  • Photoprotection is essential but must be individualized to improve adherence and effectiveness in skin of color.
  • Tinted, higher-SPF, and visible-light-protective sunscreens are often preferable, especially when hyperpigmentation is a concern.
  • Barriers such as cost, cosmetic acceptability, inadequate application, and poor reapplication limit sunscreen use in skin of color populations.
  • Secondary photoprotection agents such as polypodium leucotomos may offer additional benefit in selected photodermatoses.
  • Overall, management of photodermatoses in skin of color should emphasize accurate recognition, individualized treatment, and tailored photoprotection counseling.
  • Gutierrez D, Gaulding JV, Motta Beltran AF, Lim HW, Pritchett EN. Photodermatoses in skin of colour. J Eur Acad Dermatol Venereol. 2018 Nov;32(11):1879-1886. doi: 10.1111/jdv.15115. Epub 2018 Jul 15. PMID: 29888465.#10.1111/jdv.15115
  • Tsai J, Chien AL. Photoprotection for Skin of Color, Am J Clin Dermatol. 2022 Mar;23(2):195-205. doi: 10.1007/s40257-021-00670-z. Epub 2022 Jan 19. PMID: 35044638; PMCID: PMC8766623.#10.1007/s40257-021-00670-z
  • Garett G, Grayson CG, Rambhatla PV, Mohammad TF. A comparison of tinted sunscreen availability in an urban versus suburban setting in the Detroit area. Arch Dermatol Res. 2024.#10.21203/rs.3.rs-4504894/v1
  • Xue G, Hamzavi IH, Kohli I, Mohammad TF. Challenges of Tinted Sunscreen in Skin of Color. International Journal of Dermatology. 2024 June. Epub ahead of print.#10.1111/ijd.17347
  • Parrado and colleagues. Frontiers in Medicine. 2018. Secondary photoprotection in photodermatoses with Polypodium leucotomos extract.