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  • Presentation

Photobiomodulation Therapy for Hair Loss: MOA and How I Employ It in My Multi-Modality Hair Loss Program

Description

Dr. Rhonda Farrah discusses photobiomodulation (PBM) therapy, or low-level light therapy, for treating hair loss, particularly androgenetic alopecia. She explains the origins of PBM, highlighting its discovery in Hungary, leading to its FDA clearance in 2007. Dr. Farrah compares different light sources, such as light-emitting diodes (LEDs) and lasers, explaining their mechanisms. She notes recent findings suggesting that green light may be more effective than red light in promoting hair growth, sparking new research. Dr. Farrah emphasizes the significance of maintaining standard settings as per manufacturers' studies for optimal results, which have shown statistically significant improvements in hair counts. She reports findings from her team’s studies indicating varying responses across different demographics, including darker skin types. Importantly, she stresses compliance and realistic expectations from patients, noting that while there are benefits, results can take time. Furthermore, Dr. Farrah underscores the importance of patient education on the safety and efficacy of these devices, and the need for additional data on their application in darker skin types. Her approach combines PBM with other treatments, advocating for its use in a multi-modal strategy for hair restoration.

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Conclusions

  • Photobiomodulation devices are considered safe and effective for treating androgenetic alopecia (AGA).
  • There are variable amounts of growth factors secreted by platelets in different patients.
  • Devices for photobiomodulation should be designed to fit patient lifestyles and preferences, including affordability and discretion.
  • The efficacy of photobiomodulation increases with longer application durations, though the number of lasers used does not correlate with hair density results.
  • Photobiomodulation may be beneficial for off-label conditions like telogen effluvium and scarring alopecia, but more research is necessary.
  • Patients, especially those with lighter skin types, can benefit from photobiomodulation, and some improvements have been noted even in darker skin types despite limited data.
  • The optimal parameters for device design and usage remain unclear and continue to evolve as more studies are conducted.
  • Photodermatol Photoimmunol Photomed. 2024 Nov;40(6):e13004. doi: 10.1111/phpp.13004. Red and Green LED Light Therapy: A Comparative Study in Androgenetic Alopecia
  • J Am Acad Dermatol. 2024 Feb 1:S0190-9622(24)00186-5. doi: 10.1016/j.jaad.2023.10.073. Online ahead of print. Photobiomodulation CME Part I: Overview and Mechanism of Action
  • Am J Clin Dermatol. 2014 Apr;15(2):115-27. doi: 10.1007/s40257-013-0060-6. Efficacy and safety of a low-level laser device in the treatment of male and female pattern hair loss: a multicenter, randomized, sham device-controlled, double-blind study
  • Lasers Surg Med. 2021 Nov;53(9):1201-1207. doi: 10.1002/lsm.23411. Efficacy of Minoxidil Combined With Photobiomodulation for the Treatment of Male Androgenetic Alopecia. A Double-Blind Half-Head Controlled Trial
  • Photodermatol Photoimmunol Photomed. 2023 Nov;39(6):673-675. doi: 10.1111/phpp.12905. Use of low-level light therapy in management of central centrifugal cicatricial alopecia: A case series of four patients.
  • Clin Drug Investig. 2009;29(5):283-292.