Please login or create an account. If you do not have access to this content, you will be shown a 30 second preview and licensing options.

  • Presentation

Photo-aging: Best Evidence Based Cost-Effective Care

Description

The discussion on photo-aging emphasizes its pervasive nature as a condition experienced by everyone but not classified as a disease. The rising interest among consumers in the prevention of photo-aging is noted, highlighting a shift towards wellness in healthcare. Key topics include the impact of UV exposure on skin aging, the importance of broad-spectrum sunscreen, and the role of visible light in pigmentation issues, especially for melanocompetent individuals. Evidence-based treatments with robust data include sunscreen and topical tretinoin, both shown to significantly reduce signs of aging with level 1A evidence. The talk also covers other topical antioxidants like niacinamide and vitamin C, although caution is urged regarding the quality and efficacy of products available on the market due to variations and lack of rigorous quality control. Oral supplements, such as Polypodium leucotomos extract, are mentioned as adjunct therapies for photo-aging. The discussion concludes with the acknowledgment of the high costs associated with quality skincare products and the necessity for dermatologists to maintain an authoritative voice in the field, as skincare decisions are increasingly influenced by social media rather than scientific evidence.

View more

Conclusions

  • Photoaging is a pervasive condition that affects everyone over their lifetime although it is not classified as a true disease state.
  • Sunscreen and topical tretinoin have the most robust level 1A evidence in the prevention and treatment of photoaging.
  • UV exposure from UVA and UVB leads to DNA damage contributing to extrinsic aging and morphological changes in the skin.
  • Visible light also plays a significant role in photoaging, particularly in developing pigmentation in certain skin types.
  • Topical antioxidants like niacinamide and vitamin C can be beneficial in the repair of UV damage and improving skin texture and elasticity.
  • There is a rising consumer interest in photoaging prevention even before signs become visible, highlighting the importance of education on preventative measures.
  • The skincare industry for anti-aging products is substantial, emphasizing the need for evidence-based recommendations to avoid consumer confusion.
  • Patients should be guided to choose products based on robust scientific evidence and informed about the importance of ingredient quality and concentration.
  • Regular use of broad-spectrum sunscreens can significantly reduce signs of aging, underscoring its importance in skincare regimens.
  • Gilchrest BA (2013) Photoaging. J Invest Dermatol 133: E2-E6.
  • Am J Clin Dermatol. 2021; 22(6): 819-828.
  • Darlenski A. Br J Dermatol. 2010;163(6):1157-65.
  • Cureus. 2023 Oct 6;15(10):e46596.
  • J Drugs Dermatol. 2019 Dec 1;18(12):1198-1203.
  • J Clin Aesthet Dermatol. 2014 Mar; 7(3): 13-17.
  • N Engl J Med 2023 2;388(9):804-812.
  • Nat Commun 11, 4265 (2020).
  • Photodermatol Photoimmunol Photomed. 2017;33:156-63.
  • Photodermatol Photoimmunol Photomed. 2021 Sep 29. doi: 10.1111/phpp.12736.