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  • Presentation

Pharm to Table: Impact of Diet on Dermatologic Treatments

Description

The forum led by Vivian from the University of Arkansas focuses on the interaction between diet and dermatologic treatments, particularly how certain dietary approaches can enhance the efficacy of various treatments. She highlights the significant interest from patients in how food and supplements can support their dermatologic therapies. Key findings include the role of TNF inhibitors in weight gain among psoriasis patients and the beneficial impact of a Mediterranean diet in mitigating this while improving psoriasis severity scores and metabolic profiles. Dietary interventions like omega-3 fatty acids also demonstrate effectiveness, especially when used alongside topical vitamin D treatments to enhance outcomes in psoriasis. In atopic dermatitis, the timing of oral Jack inhibitors' absorption may be affected by meal composition, while melanoma patients on immunotherapy may benefit from high-fiber diets but should avoid oral probiotics, which may hinder their response. For actinic keratosis, vitamin D supplementation during photodynamic therapy shows promise. The discussion also encompasses the adverse effects of whey protein on acne, signaling the importance of dietary modifications, such as reducing high-glycemic foods, to support the effectiveness of isotretinoin treatments. The session emphasizes that strategic dietary adjustments can significantly impact dermatological treatment efficacy and patient well-being.

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Conclusions

  • Patients using TNF inhibitors may experience significant weight gain, which can impact their overall health outcomes.
  • A Mediterranean diet combined with TNF inhibitors can improve psoriasis severity, metabolic health, and weight management.
  • Incorporating omega-3 fatty acids into treatment can enhance the efficacy of certain therapies and may provide additional benefits for psoriasis.
  • A high fiber, low red meat diet may offer benefits for inflammatory conditions, particularly in patients with rheumatoid arthritis but shows mixed results for psoriasis.
  • For melanoma treatment, adequate dietary fiber intake improves patient response to checkpoint inhibitors and may reduce progression risk.
  • In atopic dermatitis, taking oral JAK inhibitors with a high-fat meal can significantly delay peak plasma concentration, which may affect treatment timing.
  • Vitamin D supplementation improves the efficacy of photodynamic therapy in treating actinic keratosis, especially for patients with low baseline serum levels.
  • Reducing whey protein intake may help alleviate acne symptoms in susceptible individuals, especially when combined with lower glycemic diets.
  • Including omega-3 fatty acids can reduce side effects associated with isotretinoin treatment for acne.
  • Australas J Dermatol. 2013 Nov;54(4):259-63.
  • J Dermatolog Treat. 2017 May;28(3):206-212.
  • Front Nutr. 2022 Oct 13;9:985732.
  • Br J Dermatol. 1989 Jun;120(6):801-7
  • Clin Cosmet Investig Dermatol. 2011;4:73-7.
  • Mohamed MF, et al. Br J Clin Pharmacol. doi:10.1111/bcp.13329
  • Science. 2021 Dec 24;374(6575):1632-1640.
  • JAMA Oncol. 2023 Feb 16;e227753.
  • J Am Acad Dermatol. 2022 Jul;87(1):80-86
  • J Clin Med. 2020 Feb 1;9(2):398.
  • Cutis. 2012 Aug;90(2):70-2. PMID: 22988649.
  • Eur J Dermatol. 2013 Jul-Aug;23(4):478-86.
  • Dermatol Res Pract. 2018 May 29;2018:6974045.
  • JAMA Dermatol. 2015 Jan;151(1):101-2.
  • Dermatol Ther. 2022 Mar;35(3):e15275.
  • J Clin Aesthet Dermatol. 2011 Feb;4(2):40-7.
  • Maarouf M, Platto JF, Shi VY. The role of nutrition in inflammatory pilosebaceous disorders: Implication of the skin-gut axis. Australas J Dermatol. 2019;60(2):e90-e98. doi:10.1111/ajd.12909.