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  • Presentation

Optical Imaging in the Clinic

Description

In this presentation moderated by Dr. Kristen Kelly, an expert in dermatology and imaging, the focus is on the advancements and applications of optical imaging in clinical practice. Dr. Kelly discusses non-invasive imaging technologies such as confocal microscopy and optical coherence tomography, highlighting their potential to reduce unnecessary skin biopsies, pain, and processing time. She notes that a significant percentage of biopsies might be avoidable, advocating for technologies that can assist dermatologists in making more accurate diagnoses at the point of care. The presentation covers the advantages and limitations of various imaging modalities, including their resolution, penetration depth, and practical usage in detecting conditions like melanoma and basal cell carcinoma. Artificial intelligence's role in enhancing diagnostic accuracy and guiding treatments is also addressed, emphasizing the importance of dermatologists actively participating in these advancements. Dr. Kelly concludes by underscoring the promise of non-invasive imaging in not only improving diagnosis and treatment but also in fostering the future of dermatology, advocating for dermatologists to take initiative in incorporating these technologies into everyday practice.

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Conclusions

  • Non-invasive imaging can significantly reduce the number of unnecessary skin biopsies.
  • It allows for immediate diagnosis and treatment in a single visit, improving patient outcomes.
  • Emerging imaging technologies like confocal microscopy and optical coherence tomography can enhance diagnostic accuracy.
  • Non-invasive imaging can assist in monitoring treatment progress and recurrence of skin lesions.
  • Integrating artificial intelligence with imaging can improve the identification of biomarkers and enhance diagnostic capabilities.
  • Non-invasive imaging poses minimal risk compared to traditional biopsy methods, leading to better patient satisfaction.
  • Utilizing non-invasive imaging can result in healthcare savings by reducing the need for multiple visits and procedures.
  • Eric J. Topol, MD Scripps Research Institute, La Jolla. Adapting to Artificial Intelligence Radiologists and Pathologists as Information Specialists. JAMA, December 13, 2016.
  • Schneider SL et al. Emerging Imaging Technologies in Dermatology. JAAD 20191114-1131.
  • Klaus J Busam, Ashfaq A Marghoob and Allan Halpern. Melanoma Diagnosis by Confocal Microscopy: Promise and Pitfalls. JID; 125:2005.
  • Eileen S. Flores ,* Miguel Cordova, Kivanc Kose, William Phillips, Anthony Rossi, Kishwer Nehal and Milind Rajadhyaksha. Intraoperative imaging during Mohs surgery with reflectance confocal microscopy: initial clinical experience. Journal of Biomedical Optics 20(6), 061103 (June 2015).
  • Euphemia W. Mu, MD; Jesse M. Lewin, MD; Mary L. Stevenson, MD; Shane A. Meehan, MD; John A. Carucci, MD, PhD; Daniel S. Gareau, PhD, MCR. Use of Digitally Stained Multimodal Confocal Mosaic Images to Screen for Nonmelanoma Skin Cancer. JAMA Dermatol. 2016;152(12):1335-1341.
  • Balu et. al, Biophys J. 104 258-67 (2013).
  • Balu et. al, JAMA Derm 151 (10) 1088-74 (2015).
  • Balu et. al, Cancer Res 74 (10) 2688-97 (2014).
  • Winkler JAMA Derm 159(6):621-627, 2023 (PMID: 37133847).
  • Marchetti JEADV 37(5):945-50, 2023 (PMID: 36708077).
  • Daneshjou JAMA Derm 157(11):1362-9, 2021 (PMID: 34550305).
  • Wongvibulsin JAMA Derm 160(6):646-650, 2024 (PMID: 38452263).