Opportunistic Infections and Drug Rashes Oh My - Managing the Cutaneous Complications of Solid Organ Transplantation

The presentation discusses managing cutaneous complications associated with solid organ transplantation, specifically focusing on opportunistic infections and drug rashes. Dr. Gallitano and Dr. Whitley address the history and evolution of transplant medicine, highlighting the immunosuppressive regimens used to prevent organ rejection and their resultant side effects. Key points include the heightened risk of opportunistic infections due to impaired immune response in transplant patients, with a prevalence of viral infections such as cytomegalovirus (CMV) and human papillomavirus (HPV). Various cutaneous manifestations from immunosuppressive therapies, like steroid acne and hair loss from tacrolimus, are discussed. The session emphasizes the importance of diagnosing and managing skin complications effectively, considering both classic and emerging therapies. Cutaneous viral infections, particularly those related to HPV and human polyomavirus, require close monitoring and the use of treatments ranging from topical therapies to systemic medications. Dr. Whitley highlights the significance of multidisciplinary care in managing these complex patients and illustrates practical management strategies. The talk concludes by emphasizing the continuing need for research and collaboration in the field of transplant dermatology, ensuring optimal patient outcomes.