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- Presentation
New Innovations in Treatment of Subcutaneous and Visceral Fat
Description
The presentation discusses recent innovations in the treatment of subcutaneous and visceral fat, specifically focusing on a new injectable technology called ice slurry. Initially, the talk highlights selective cryolipolysis, a non-invasive technique developed by researchers that uses controlled cooling to selectively target and reduce fat by inducing cold-induced injury in lipid-rich tissues. The ice slurry method offers advantages over traditional topical cooling, as it is faster, more effective by directly targeting fat, and customizable. Evidence from studies in swine demonstrates that ice slurry injections can lead to significant fat loss (around 50% after one injection) while sparing surrounding tissues. This technique is also being explored to target deeper visceral fat, which is linked to various health risks. In animal studies with mice and rats, the injectable method indicated a notable reduction in visceral fat, promoting potential weight loss and using controlled apoptosis to minimize side effects. This promising technology has also been tested on cardiac visceral fat in a swine model, showing a successful reduction of approximately 30% in fat without affecting surrounding tissues. The speaker emphasizes the significant clinical potential of this injectable cryolipolysis technology in addressing health issues related to excess visceral fat.
View moreConclusions
- Injectable ice slurry technology is a more efficient and effective method for reducing subcutaneous and visceral fat compared to traditional topical cooling techniques.
- A single injection of ice slurry can lead to approximately 50% fat loss in subcutaneous fat within eight weeks, as evidenced by ultrasound imaging findings.
- The mechanism of fat loss through the injectable ice slurry involves controlled apoptosis, minimizing side effects typically associated with fat reduction methods.
- Visceral fat, particularly around the organs, can also be targeted using this injectable method, leading to significant reductions without damaging adjacent tissues.
- This technology holds promise for addressing obesity-related health issues by selectively reducing both subcutaneous and visceral fat, potentially aiding in weight loss and improving metabolic health.
- Garibyan L, et al. Subcutaneous Fat Reduction with Injected Ice Slurry. Plast Reconstr Surg. 2020 Jan 7.
- Shuhaiber J et al. Lasers Surg Med. 2023 Sep;55(7):674-679.