Please login or create an account. If you do not have access to this content, you will be shown a 30 second preview and licensing options.

Presentation

Late Breaking Cosmeceuticals 2024

Description

The presentation by Doctor Drelo emphasizes the latest advancements in skincare, focusing on innovative ingredients rather than brand names. Key highlights include a novel hyaluronic acid formula featuring dual molecular weights that enhance hydration and skin radiance, as well as a new acetyl dipeptide targeting pigmentation and laxity, showing promising clinical results. The use of Lotus sprout extract for effective skin brightening is discussed, revealing mechanisms that enhance melanosome phagocytosis without harming cells. Additionally, a new liposomal form of vitamin C offers enhanced stability and penetration while contributing to improved skin elasticity and antioxidant protection. Turmeric is highlighted for its antioxidant properties in lip products with minimal impact on the microbiome. The talk also addresses advanced glycation end products, showcasing a fruit flavonoid complex that improves collagen health. A hydroquinone alternative, Melacillin, is introduced, effectively reducing pigmentation without the associated risks of hydroquinone. Lastly, TPH-E is noted for its skin-firming properties, while a new hybrid sunscreen caters to individuals with darker skin tones, demonstrating significant improvements in hyperpigmentation. These developments offer exciting possibilities for enhancing skin health and appearance.

View more

Conclusions

The novel multi-weight hyaluronic acid formulation with antioxidants significantly improves skin dryness, roughness, fine lines, and radiance compared to single-weight formulations.
The new peptide cream showed clinical improvements in sagging, discoloration, and overall skin photodamage over 16 weeks.
Lotus sprout extract enhances melanosome degradation and offers a distinctive skin brightening mechanism without affecting cell nuclei.
Optimized tranexamic acid formulations demonstrate significant improvements in skin tone evenness and hyperpigmentation over time, comparable to 4% hydroquinone but with fewer irritations.
A new liposomal vitamin C effectively combats free radical damage and maintains elastin, achieving noteworthy reductions in fine lines and hyperpigmentation after 12 weeks.
Turmeric lip treatments exhibit strong antioxidant and anti-inflammatory effects without disrupting the skin microbiome.
Advanced glycation end products (AGEs) degrade collagen, and new antioxidant-rich formulations with wild fruit extracts inhibit AGE formation and improve skin elasticity.
The innovative skin-lightening agent 2-MNG displays rapid efficacy in reducing pigmentation without influencing surrounding skin tone.
TPHE, a new skin firming ingredient, induces immediate tightening effects and improves facial contours post-application.
A novel sunscreen tailored for skin of color effectively reduces hyperpigmentation while enhancing overall skin appearance and moisturization.

Galderma, Data on file.
Canfield Scientific Inc., Parsippany, NJ.
1. Preventing & Treatment Advanced Glycation End Products.
5. Oxidative stress caused by UV exposure increases A.G.E ., with 10% higher AGE accumulation in tissues.