Please login or create an account. If you do not have access to this content, you will be shown a 30 second preview and licensing options.

  • Presentation

Itch Tales: Psoriasis

Description

The talk addresses the complexities of diagnosing and managing psoriasis, emphasizing the challenge of distinguishing it from eczema due to overlapping features, particularly in the context of itch. A case study of a 54-year-old female with a long history of psoriatic arthritis illustrates these diagnostic challenges; her seemingly eczematous rash prompted a misdiagnosis initially. The speaker highlights that itch is a prevalent symptom among psoriasis patients, often more so than redness or scaling, and can severely impact quality of life. The discussion emphasizes that itch in psoriasis is not merely a differentiating factor for eczema but can be indicative of disease severity. The talk also illustrates that itch can worsen psoriasis through scratching, potentially leading to worse disease outcomes. Various histopathological overlaps between psoriasis and eczema make diagnoses complicated, and often a clinical approach with careful patient interviews is necessary to identify the correct treatment path. Ultimately, it stresses that while psoriasis typically has clear diagnostic criteria, the considerable role of itch requires attentive management to enhance patient well-being and disease control.

View more

Conclusions

  • Distinguishing between psoriasis and eczema can be challenging due to overlapping clinical features and histopathological findings.
  • Itch is a predominant and often under-recognized symptom in psoriasis, reported as the most troublesome by patients.
  • Psoriasis patients, especially those with milder disease, often experience itch, which can significantly impact their quality of life.
  • Management of itch is crucial as it can exacerbate psoriasis severity through mechanisms like Koebnerization.
  • Psychosocial factors, such as stigmatization and stress, are compounded by itch in psoriasis patients, leading to heightened emotional distress.
  • Sleep disturbance caused by itch can create a pro-inflammatory state, potentially worsening psoriasis pathology.
  • Comprehensive evaluation of itch can guide treatment decisions and therapeutic adjustments in psoriasis management.
  • Noorily et al. The American Journal of Dermatopathology43(2):112-118, February 2021.
  • Lai et al. JAMA Dermatol. 2019 Sep 1;155(9):1082-1084.
  • Park et al. J Am Acad Dermatol. 2017 Jul;77(1):130-135
  • Posada et al. Actas Dermosifiliogr. 2010 Jan-Feb;101(1):103-5.
  • Lebwohl et al. JAAD 2014. 70(5): 871-881.e30.
  • Elewski et al. JEADV. Aug 2019. 33(8): 1465-1476.
  • Globe et al. Health Qual Life Outcomes. 2009 Jul 6:7:62.
  • Shahwan et al. JAAD. Jun 2017. 76(6): 1198-1200. e1
  • Zhu et al. Br J Dermatol 2014; 171(5): 1215-1219
  • Reich A, et al. Acta Derm Venereol 2010; 90: 257-263.
  • O'Neill et al. Acta Derm Venereol 2011; 91: 537-540
  • Kimball et al. J Drugs Dermatol 2016 Feb;15(2):183-8.
  • Lavery et al. Acta Derm Venereol. 2017 Apr 6;97(4):513-515.
  • Hirotsu et al. PLOS One. 2012; 7(11). e51183.
  • Bellinato F, et al. Biologics. 2021;15:247-253.