Please login or create an account. If you do not have access to this content, you will be shown a 30 second preview and licensing options.
- Presentation
Intralesional Sodium Thiosulfate Injections and Clinical Pearls for the Management of Calcinosis Cutis in Connective Tissue Disease Patients
Description
Dr. Anne Morano discusses the management of calcinosis cutis in connective tissue disease patients, particularly through the use of intralesional sodium thiosulfate (STS) injections. She emphasizes the need to evaluate each patient for new lesions, which may require adjustments in their treatment plans. The presentation covers the procedure for STS injections, noting that it can alleviate symptoms but is not a cure, and explores adjunctive treatment options, including topical therapies and antibiotics. Dr. Morano explains the procedural details, including proper anesthetic use and post-procedure care, and presents patient case studies that highlight the effectiveness of the treatment in reducing calcinosis. She stresses the importance of medical optimization and patient education regarding potential side effects such as ulceration. Ultimately, she concludes that while calcinosis cutis is challenging to treat, an integrated approach using STS and supportive therapies can lead to significant improvements.
View moreConclusions
- Calcinosis cutis in connective tissue disease patients is challenging to manage, often due to prior inflammation.
- Sodium thiosulfate (STS) injections are effective for treating calcinosis cutis, particularly in CREST and scleroderma patients.
- Medical optimization of underlying conditions can improve symptoms and quality of life for patients.
- Topical STS (10-20% ointment) may be beneficial in managing calcinosis and should be considered in treatment plans.
- The intralesional STS procedure requires careful patient evaluation, including pain management with local anesthesia and antibiotics for potential ulcerations.
- Patients generally appreciate any improvements in quality of life from treatments, even if they are not cures.
- Expect continuous follow-up treatment until improvement plateaus, typically after 2-3 months.