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  • Presentation

Intralesional Scalp Treatments for Hair Loss

Description

This presentation discusses intralesional scalp treatments for hair loss, focusing on methods like mesotherapy and micro-needling therapy (MMP). The speaker highlights that combining various treatments can enhance results for patients suffering from androgenetic alopecia (AGA), especially those resistant to standard therapies. Mesotherapy involves injecting medications, notably minoxidil and finasteride, and while evidence of efficacy is limited, it is increasing. Details on the injection process are shared, including specific volumes and techniques to ensure comfort during the procedure. The speaker mentions the occurrence of minor side effects, with sensitivity being a common issue after treatment. An important caution was raised regarding potential adverse effects linked to specific medications used in mesotherapy, signaling recent reports of complications. MMP, described as using a tattoo machine to deliver medications into the skin in a gentle manner, is noted as an alternative approach with similar medication protocols and shorter session times. The need for ongoing sessions and coordinating them with oral treatments is emphasized. The speaker concludes with gratitude, summarizing effective strategies for managing AGA through these innovative intralesional techniques.

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Conclusions

  • Intralesional treatments, including mesotherapy and MMP, show potential benefits for managing androgenetic alopecia.
  • Combining different treatment modalities may improve outcomes for advanced cases or poor responders to standard therapies.
  • There is evidence supporting the use of minoxidil and dutasteride in mesotherapy, but the overall research is still developing.
  • Protocols for mesotherapy typically involve multiple sessions spaced over weeks, with variations based on individual patient needs.
  • MMP offers a novel method for drug delivery with benefits associated with micropigmentation techniques.
  • Care must be taken regarding the preparation and quality of medications used in mesotherapy to avoid adverse effects.
  • Patients can expect some side effects, such as sensitivity and mild pain, but severe complications are rare when procedures are performed correctly.
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  • J Eur Acad Dermatol Venereol. 2013 Jun;27(6):686-93. doi: 10.1111/j.1468-3083.2012.04535.x.
  • Int J Trichology. Jul-Sep 2017;9(3):143-145. doi: 10.4103/ijt.ijt_73_16. Mesotherapy with Dutasteride in the Treatment of Androgenetic Alopecia preparation in treatment of female pattern hair loss: photographic, morphometric and ultrustructural evaluation.
  • Int J Dermatol. 2019 Jun;58(6):750-755. doi: 10.1111/ijd.14408. Epub 2019 Mar 3. How much medication is delivered in a novel drug delivery technique that uses a tattoo machine?
  • J Am Acad Dermatol. 2018 Jan;78(1):212-215. doi: 10.1016/j.jaad.2017.08.019. Randomized Controlled Trial.
  • JAAD Int. 2021 Mar 6;3:14-16. doi: 10.1016/j.jdin.2021.01.005. eCollection 2021 Jun. Treatment of idiopathic guttate hypomelanosis with a tattoo device versus a handheld needle.