Immunostaining in Mohs Surgery: Impact, Interpretation, and Implementation

In the discussion about immunostaining in Mohs surgery, Dr. Jeff Lim highlights its significance in enhancing patient care while also addressing the financial sustainability of implementing such techniques in various practice settings. He offers a primer aimed at equipping practitioners with the knowledge to integrate immunostaining into their own labs cost-effectively. The talk covers the essential who, what, where, how, and why of immunostaining, beginning with the necessary tools and reagents, including a focus on the Mart-1 stain crucial for cases like erosive Ectopic Melanoma (EMPD). Dr. Lim emphasizes the importance of proper training, technique modification, and effective documentation in ensuring reproducibility and quality control in a laboratory setting. He discusses the economic viability of introducing immunostaining, noting the costs associated with each case against potential reimbursements, illustrating that while there is opportunity for practice growth through improved patient care, financial feasibility must also be critically assessed. Ultimately, he acknowledges both the tangible and intangible benefits of adding this service line, positioning it as a valuable differentiation factor for practices aiming to expand their offerings amidst an evolving healthcare landscape.