Please login or create an account. If you do not have access to this content, you will be shown a 30 second preview and licensing options.

  • Presentation

Great Care for Common Conditions: Combining Evidence and Cost Effectiveness

Description

The presentation, led by a dermatology expert, focuses on the cost-effective management of acne through a combination of evidence-based practices and pragmatic recommendations. Despite the evolving landscape of acne treatment research, there remains a gap in comprehensive data, particularly regarding cost-effective solutions. The speaker highlights key recommendations from the new American Academy of Dermatology guidelines, emphasizing the benefit of combination therapies to improve adherence and potentially reduce costs. Simple strategies, like advising patients to wash their faces twice daily, manage sugar intake, and recommending over-the-counter options like clay masks, are proposed as low-cost interventions that can support acne treatment. A notable discussion around spironolactone showcases its effectiveness and affordability, particularly in women, while also cautioning that a significant subset of younger females may not respond to it. The guidelines are framed as flexible suggestions for healthcare providers to enhance patient care, reinforcing the importance of considering both clinical efficacy and financial implications in treatment planning.

View more

Conclusions

  • Coordinated evidence-based guidelines for acne management have been published, which include cost considerations.
  • Washing the face twice daily can lead to noticeable improvements in acne, particularly for comedones and non-inflammatory lesions.
  • Dietary changes, particularly reducing sugar intake, may positively affect acne severity.
  • Combination therapies, such as fixed-dose products, have shown better outcomes and adherence in patients.
  • Spironolactone has been found to be effective and cost-effective for treating adult women with persistent acne.
  • Laboratory monitoring for spironolactone may be unnecessary for many patients, reducing healthcare costs.
  • Oral isotretinoin is strongly recommended for severe cases of acne due to its high effectiveness despite its cost.
  • In adolescents, a significant percentage may not respond to spironolactone, indicating that it may not be a universal solution.
  • Affordable alternatives, such as topical prescriptions like benzoyl peroxide and clindamycin, can be effective for mild to moderate acne.
  • Pediatric Dermatology. 23(5):421-7, 2006 Sept-Oct.
  • Reynolds RV, Yeung H, Cheng CE, Cook-Bolden F, Desai SR, Druby KM, Freeman EE, Keri JE, Stein Gold LF, Tan JKL, Tollefson MM, Weiss JS, Wu PA, Zaenglein AL, Han JM, Barbieri JS. J Am Acad Dermatol. 2024 May;90(5):1006.e1-1006.e30. doi: 10.1016/j.jaad.2023.12.017.
  • Mavranezouli I, Welton NJ et al. Cost-effectiveness of topical pharmacological, oral pharmacological, physical and combined treatments for acne vulgaris. Clin Exp Dermatol. 2022 Dec;47(12):2176-2187.
  • Sun HY, Deshan F Sebaratnam DF. Assessment of disutility in cost-effectiveness analyses in acne. Clin Exp Dermatol. 2023 Mar 1;48(3):242-243.
  • Pyne S, Tracey H Sach TH. Cost-effectiveness of Spironolactone for Adult Female Acne (SAFA): economic evaluation alongside a randomised controlled trial. BMJ Open. 2023 Dec 11;13(12):e073245.
  • Santer M, Lawrence M, Pyne S. Clinical and cost-effectiveness of spironolactone in treating persistent facial acne in women: SAFA double-blinded RCT. Health Technol Assess.2024 Sep;28(56):1-86.
  • Roberts EE, Nowsheen S, Davis DMR, Hand JL, Tollefson MM, Wetter DA. Use of spironolactone to treat acne in adolescent females. Pediatr Dermatol. 2020 Oct 3.
  • Zhang X, Zhongxing Zhang Z et al. Comprehensive assessment of the efficacy and safety of a clay mask in oily and acne skin. Skin Res Technol. 2023 Nov;29(11):e13513.