Please login or create an account. If you do not have access to this content, you will be shown a 30 second preview and licensing options.
- Presentation
Epidemiology of Pediatric Hidradenitis Suppurativa (HS): Now a Pediatric Disease
Description
The presentation by Jen Ruth from UT Austin focuses on the epidemiology of pediatric Hidradenitis Suppurativa (HS), highlighting its emergence as a significant pediatric condition. It begins by defining epidemiology and noting a substantial increase in research studies on HS, particularly pediatric cases, which have grown fourteenfold in recent years. The statistics suggest a prevalence rate of about 28 per 100,000 in the general pediatric population, with notably higher rates among African American and biracial females aged 15 to 17. The analysis reveals that many patients experience delays in diagnosis, often already presenting with scarring when first evaluated by dermatologists. Factors such as family history, obesity, and common comorbidities like acne vulgaris exacerbate the condition, particularly in special populations like those with Down syndrome. The speaker emphasizes the need for continued research and education to improve recognition and management of pediatric HS, advocating for better awareness among healthcare providers and the inclusion of diverse populations in research efforts. Ultimately, the presentation recommends a comprehensive approach to elevate understanding and treatment of pediatric HS, stressing that the true prevalence and impact of the disease may be underestimated due to these ongoing challenges.
View moreConclusions
- The prevalence of pediatric hidradenitis suppurativa (HS) is estimated to be around 28 per 100,000, but it is likely higher due to underreporting and undiagnosed cases.
- Significant delays in diagnosis and recognition of pediatric HS are common, leading to advanced scarring in patients by the time they receive care.
- Pediatric HS affects certain subpopulations disproportionately, particularly African American and biracial females aged 15 to 17 years.
- There is a notable comorbidity burden associated with pediatric HS, including high rates of obesity, acne, and mental health issues.
- Increased awareness, education, and research are critical for improving diagnosis and care for pediatric HS.
- Some pediatric patients, especially those with Down syndrome, show a markedly higher prevalence and earlier onset of HS.
- Denny G, Anadkat MJ. Hidradenitis suppurativa (HS) and Down syndrome (DS): Increased prevalence and a younger age of hidradenitis symptom onset. J Am Acad Dermatol. 2016 Sep;75(3):632-634. doi: 10.1016/j.jaad.2016.04.045. PMID: 27543219.
- Garg A, Wertenteil S, Baltz R, Strunk A, Finelt N. Prevalence Estimates for Hidradenitis Suppurativa among Children and Adolescents in the United States: A Gender- and Age-Adjusted Population Analysis. J Invest Dermatol. 2018 Oct;138(10):2152-2156. doi: 10.1016/j.jid.2018.04.001. Epub 2018 Apr 13. PMID: 29660301.
- Hallock KK, Mizerak MR, Dempsey A, Maczuga S, Kirby JS. Differences Between Children and Adults With Hidradenitis Suppurativa. JAMA Dermatol. 2021 Sep 1;157(9):1095-1101. doi: 10.1001/jamadermatol.2021.2865. PMID: 34379074; PMCID: PMC8358812.
- Ingram JR. The epidemiology of hidradenitis suppurativa. Br J Dermatol. 2020 Dec;183(6):990-998. doi: 10.1111/bjd.19435. Epub 2020 Sep 3. PMID: 32880911.
- Ingram JR, Jenkins-Jones S, Knipe DW, Morgan CLI, Cannings-John R, Piguet V. Population-based Clinical Practice Research Datalink study using algorithm modelling to identify the true burden of hidradenitis suppurativa. Br J Dermatol. 2018 Apr;178(4):917-924. doi: 10.1111/bjd.16101. Epub 2018 Feb 22. PMID: 29094346.
- Kirby JS, Zaenglein AL. Recognizing the Effects and Disparities of Pediatric Hidradenitis Suppurativa. JAMA Dermatol. 2021 Apr 1;157(4):379-380. doi: 10.1001/jamadermatol.2020.5434. PMID: 33625471.
- Lam M, Lai C, Almuhanna N, Alhusayen R. Hidradenitis suppurativa and Down syndrome: A systematic review and meta-analysis. Pediatr Dermatol. 2020 Nov;37(6):1044-1050. doi: 10.1111/pde.14326. Epub 2020 Sep 6. PMID: 32892406.
- Liy-Wong C, Pope E, Lara-Corrales I. Hidradenitis suppurativa in the pediatric population. J Am Acad Dermatol. 2015 Nov;73(5 Suppl 1):S36-41. doi: 10.1016/j.jaad.2015.07.051. PMID: 26470613.
- Offidani A, Molinelli E, Sechi A, Brisigotti V, Campanati A, Raone B, Neri I, Patrizi A. Hidradenitis suppurativa in a prepubertal case series: a call for specific guidelines. J Eur Acad Dermatol Venereol. 2019 Oct;33 Suppl 6:28-31. doi: 10.1111/jdv.15827. PMID: 31535767.
- Palmer RA, Keefe M. Early-onset hidradenitis suppurativa. Clin Exp Dermatol. 2001 Sep;26(6):501-3. doi: 10.1046/j.1365-2230.2001.00876.x. PMID: 11678875.