Please login or create an account. If you do not have access to this content, you will be shown a 30 second preview and licensing options.
- Presentation
Emerging Allergens
Description
The presentation discusses emerging allergens in contact dermatitis, focusing on significant allergens like Isothiazolanones, sulfites, botanical allergens, acrylates, and propylene glycol. It highlights the ongoing impact of Isothiazolanones in North America, noting a potential stabilization or decline in patch test positivity. Attention is drawn to the complexity surrounding Benzoisothiazolone (BIT), its presence in industrial products, and the potential for cross-reactivity. Furthermore, sulfites, which may result in dermatitis, especially in occupational settings, are described as increasingly recognized allergens with significant clinical relevance. The speaker urges clinicians to inquire about cosmetic and personal care products linked to sulfite exposure. Botanical allergens like hydroperoxide of linalool and propolis are noted for their rising incidence in contact dermatitis cases, particularly due to their inclusion in cosmetics. The rise of acrylates, related to trends in nail and beauty treatments, is discussed, emphasizing their potential for sensitization. Lastly, the presentation underscores the importance of recognizing propylene glycol as a common irritant in topical products and medications. Overall, clinicians are encouraged to consider these emerging allergens in their practice and use comprehensive testing strategies to improve patient outcomes.
View moreConclusions
- The prevalence of contact dermatitis due to isothiazolinones remains significant, though there's evidence that the epidemic may be stabilizing or decreasing.
- Cross-reactivity and potential irritant reactions may complicate diagnoses related to benzo isothiazolinone (BIT).
- Sulfites are likely under-recognized as allergens, particularly in contexts involving hand and facial dermatitis.
- Botanical allergens such as hydroperoxides of linalool and propolis should be tested routinely due to their rising incidence of allergy.
- ACD (Allergic Contact Dermatitis) related to acrylates is increasing, linked to the growing popularity of beauty products and procedures involving these compounds.
- Propylene glycol is a common irritant and sensitizer in a wide range of personal care products, necessitating caution in dermatologic prescriptions.
- Reeder et al, JAAD (2024)
- Geier et al, Contact Dermatitis (2021)
- Dekoven et al, Dermatitis (2023)
- Chew and Maibach, Contact Dermatitis (2006)
- Norman et al. Dermatitis (2023)
- Goodier et al, Dermatitis (2019)
- Bai et al, Dermatitis (2020)
- Famele et al, Contact Dermatitis (2022)
- Aerts et al, Eur J Dermatol (2017)
- Ruggiero and Neeley, Dermatitis (2021)
- Ekstein and Warshaw, Dermatitis (2023)
- Garcia-Gavin et al (2012)
- Ralph et al (2015)
- Warshaw et al (2021)
- Haberle et al (2016)
- Hamann et al, Contact Dermatitis (2022)
- Dendooven et al, BID (2020)
- Metcalfe et al. Food Allergy: Adverse Reactions to Foods and Food Additives. (2014)
- Daftary et al, Dermatitis (2023)
- Krijl et al, Contact Dermatitis (2022)
- Ung et al, BJD (2018)
- Elliot et al, 2017
- Natsch et al, 2019
- Kern et al, 2014
- Sukakul et al, Dermatitis (2024)
- Dhaliwal et al, BJD (2019)
- Raison-Peyron and Dereure, Contact Dermatitis (2019)
- Malinauskiene et al, Contact Dermatitis (2019)
- Faulker et al. JPRAS (2021)
- Gregoriou et al, Dermatitis (2020)
- Guenther et al, Dermatitis (2023)
- Murphy & Brown, Dermatitis (2022)
- Shawa et al, Dermatitis (2023)
- Ulriksdotter et al, BJD (2022)
- Sasseville, Dermatitis (2012)
- Nakagawa et al, EJD (2022)
- Mcgowan et al, Dermatitis (2018)