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  • Presentation

Dermatology Case Discussion: Follicular Dermatoses and Diagnostic Differentials

Description

This dermatology case discussion presented two follicular dermatoses with important diagnostic pitfalls. The first case involved a 38-year-old man from Rwanda with a two-year history of intensely pruritic, shiny, scaly lower legs with follicular pustules, hair loss, and a nonspecific biopsy showing suppurative folliculitis. The diagnosis was dermatitis curis pustulosa atrophicans, a chronic folliculitis seen mainly on the lower legs of young men in tropical regions, associated with Staphylococcus aureus and sometimes emollient use, which can progress from pustules to scarring alopecia and tends to be treatment-resistant. The second case was a 55-year-old man with a chronic scaly eruption on the extremities and abdomen. Biopsy showed epidermal hyperplasia, follicular plugging, shoulder parakeratosis, mild inflammation, and neutrophils, initially suggesting seborrheic dermatitis, but the clinical pattern and expert review supported follicular psoriasis. The speaker emphasized that follicular psoriasis is likely underrecognized, often occurs in females with darker skin, may present with or without classic plaque psoriasis, and should be considered in the differential when shoulder parakeratosis is seen, along with PRP and other follicular disorders.

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Conclusions

  • Dermatitis cruris pustulosa et atrophicans appears to be a chronic pruritic superficial folliculitis of the lower legs in young men from tropical settings that can progress from pustules to scaly, atrophic scarring alopecia.
  • The condition is likely multifactorial, with Staphylococcus aureus, occlusion, trauma, and possibly heavy emollient use or traditional practices contributing to its development or persistence.
  • Histopathology in dermatitis cruris pustulosa et atrophicans is often nonspecific but usually shows suppurative folliculitis and hyperkeratosis.
  • The disease tends to be refractory to treatment, so management focuses on topical or systemic antibiotics when needed and, importantly, removing provoking factors.
  • Follicular psoriasis is probably underrecognized and may present either alone or alongside classic plaque psoriasis, especially in females with dark skin.
  • Follicular psoriasis can clinically mimic several other papular or follicular disorders, so it belongs in the differential for chronic scaly follicular eruptions.
  • Its histology is not highly specific, but follicular plugging, shoulder parakeratosis, hypogranulosis, and perifollicular inflammation are supportive clues.
  • A key takeaway is that shoulder parakeratosis should not automatically be attributed to seborrheic dermatitis, because PRP and follicular psoriasis are also important possibilities.
  • Dermatitis Cruris Pustulosa et Atrophicans: Scarring Alopecia Beyond Scalp Hair#10.1159/000521267
  • Follicular psoriasis: an under-reported entity. A report of five cases#10.1046/j.1365-2133.1997.19992080.x
  • A Clinical, Dermoscopic, and Histopathological Study of Follicular Psoriasis#10.4103/ijt.ijt_168_20
  • Cover Quizet in J Cutan Pathol. 2013 Oct;40(10):859-62. David P. Arps, Conroy Chow, Lori Lowe, and May P. Chan