Please login or create an account. If you do not have access to this content, you will be shown a 30 second preview and licensing options.
- Presentation
Correlations Between Dermoscopy and Histology in Dermatopathology
Description
The presentation explores the intricate relationship between dermoscopy and histology in dermatopathology, emphasizing their diagnostic correlations. The speaker illustrates the challenges faced when clinical and histological findings do not align, sharing cases that range from unusual pigmented nail lesions to various melanomas. Unique dermoscopic features, such as pseudopods and the negative pigment network are discussed, highlighting their implications in diagnosing melanoma. The necessity of adequate tissue sampling and orientation during biopsy procedures is stressed to avoid misinterpretation of lesions. Different dermatoscopic patterns, including those seen in Spitz nevi and other skin lesions, are compared to malignant conditions, showcasing the importance of understanding how these features correlate with histopathology. The talk concludes with reflections on the necessity for clinicians and pathologists to communicate effectively, ensuring comprehensive evaluation and accurate diagnosis, ultimately benefiting patient management.
View moreConclusions
- Dermoscopy can reveal unexpected patterns that may lead to a revised diagnosis in cases of skin lesions.
- Histological evaluations can sometimes show less dramatic changes than expected based on clinical and dermoscopic findings.
- It is important to bisect and properly orient specimens to minimize sampling errors and obtain accurate histological correlations.
- Negative pigment networks observed in dermoscopy can indicate melanoma, especially when arising from a nevus.
- Superficial spreading melanoma may present with distinct dermoscopic features such as pseudopods and radial streaming.
- When pathology and clinical assessments do not match, further investigation is warranted, including deeper sectioning for histology.
- Chrysalis structures in histology can indicate dermal fibrosis and immune responses to tumors, differing from patterns seen in melanoma.
- Dowdle TS, Fenner B, Maldonado D, Purser J, Tarbox M. Longitudinal Erythronychia Secondary to a Wooden Splinter. Review began 11/22/2022; Review ended 01/09/2023; Published 01/10/2023. Dermatology, Texas Tech University Health Sciences Center School of Medicine, Lubbock, USA.
- Shitara H, et al. Negative pigment network associated with melanoma. (2015)
- Pizzichetta MA, et al. Am J Dermatopathol. 2014 May;36(5):433-8.