Complications of Dermal Fillers in Autoimmune and Immuno-mediated Diseases

In a presentation on the complications of dermal fillers in patients with autoimmune and immuno-mediated diseases, dermatologist Maya Yanis discusses the risks and challenges faced by these patients when considering filler injections. Engaging the audience, she highlights that while some guidelines suggest avoiding fillers in cases of active autoimmune diseases, patients with inactive conditions may be treated at the physician's discretion. A significant finding from her research, involving 338 patients, reveals an 8% complication rate and a 6.1% rate of disease reactivation, although the latter's direct causation by fillers remains uncertain. She emphasizes that complications associated with hyaluronic acid fillers are comparable to those involving collagen biostimulators and that current treatments such as biologics do not seem to increase risk. The discussion includes the potential benefits of immunosuppressants and biologics, suggesting they may help manage filler complications. However, the risk of infections, particularly in patients on corticosteroids and certain biologics, calls for careful monitoring and infection prevention strategies. Ultimately, she underscores the importance of informed decisions between physicians and patients, advocating individualized approaches based on disease status and treatment history.