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- Presentation
Complex Medical Dermatology in People Living with HIV
Description
The presentation, led by a dermatologist with a focus on HIV-related dermatology, highlights the evolving understanding of skin manifestations in individuals living with HIV. It emphasizes the impact of HIV on immune dysregulation, which leads to various dermatoses, including opportunistic infections, inflammatory conditions like psoriasis and atopic dermatitis, and hormonal changes influencing immune responses. The talk covers the global landscape of HIV, specifically the Botswana program's success in managing HIV through effective antiretroviral therapy. It addresses the significant increased risk of skin cancers, particularly Kaposi sarcoma among HIV patients, and urges clinicians to conduct regular screenings. Various case studies illustrate common presentations such as medication-induced Stevens Johnson syndrome, systemic infections, and inflammatory dermatoses, stressing the importance of accurate diagnosis and treatment adjustments for HIV-positive patients. The speaker emphasizes biologics' safety for managing conditions like atopic dermatitis and psoriasis, advocating for proactive management strategies to enhance patient care in dermatology for those living with HIV, while acknowledging the complexities of treatment in immunocompromised individuals. The presentation concludes with case studies illustrating diverse dermatological challenges and the importance of tailored approaches in managing skin health in HIV patients.
View moreConclusions
- HIV-associated dermatological manifestations are significantly influenced by T cell immune dysregulation.
- HIV has been linked to an increased risk of various skin cancers, particularly Kaposi sarcoma.
- Post-HAART, the incidence of opportunistic infections and inflammatory dermatoses has changed, demonstrating a notable shift.
- Effective treatment with HAART has been associated with improved overall dermatological health in HIV patients.
- Higher CD4 counts are linked to fewer severe skin infections, while lower counts result in a greater variety of dermatological conditions.
- Certain skin conditions, such as psoriasis and atopic dermatitis, may worsen due to HIV infection and non-compliance with treatment.
- Inflammatory and infectious skin disorders continue to affect HIV-positive individuals, indicating ongoing needs for dermatological care.
- Diagnosis of skin conditions may serve as a critical opportunity to identify HIV infection, especially in atypical presentations.
- There seems to be an emerging pattern of chronic dermatological conditions in HIV patients as viral loads decrease and treatment improves.
- Blood circulation HIV infectious TEM in circulation
- HIV-Associated Immune Dysregulation in the Skin: A Crucible for Exaggerated Inflammation and Hypersensitivity
- REVIEW Inflammatory skin disorders HIV-Associated Immune Dysregulation in the Skin: A Crucible for Exaggerated Inflammation and Hypersensitivity
- 25 YEARS OF HAART 2021: https://www.positivelyaware.com/articles/25-years-haart
- Joint United Nations Programme on HIV/AIDS UNAIDS
- Patterns of Skin Disease in the Context of a High Prevalence
- Source: Omland S et al. J Am Acad Dermatol. 2018 Mar 24. pll: S0190-9622(18)30475-4. Skin cancer risk in people living with HIV: a call for Jacob P Reinhart MD and Kieron S Leslie MBBS
- Robert Bobotsis, MD, MSc(SLI), Shakira Brathwaite, MD, MSc, Panteha Eshtiaghi, MD, Fabian Rodriguez-Bolanos, MD, Philip Doiron, BSc, MSc, MD* Division of Dermatology, Department of Medicine, Faculty of Medicine, University of Toronto School of Medicine, Toronto, Ontario, Canada
- IDCases, 2023; 31: e01660. Published online 2022 Dec 5. doi: 10.1016/j.idcr.2022.e01660
- PMID: 36197426; Sample photo of condition from visualdx.com Case photo in next slide!
- Review > Front Pharmacol. 2021 Apr 26;12:588063. doi: 10.3389/fphar.2021.588063.
- A Case of Disseminated Cutaneous Herpes Simplex Virus-I as the First Manifestation of Human Immunodeficiency Virus Infection
- Published online 2022 Sep 30. doi: 10.1590/S1678-9946202264065
- EXAMPLES OF CAPTURE DATES: 2022
- Drug Saf Case Rep. 2015 Dec; 2(1): 15. PMCID: PMC5005653. Published online 2015 Sep 24. doi: 10.1007/s40800-015-0019-z
- Bey Inst Med Trop Sao Paulo, 2022; 64: e65.