Clinicopathologic Self-Assessment Session

The session discusses a clinicopathologic self-assessment with three dermatological cases. The first case concerns a three-day-old female with a blistering eruption diagnosed as incontinentia pigmenti (IP), characterized by intra-epidermal vesicles and eosinophilic spongiosis. The discussion covers the key histological findings and autoantibody mechanisms causing IP, along with possible misdiagnoses, including bullous pemphigoid and scabies. The second case involves a middle-aged female with unilateral retiform purpura on the knee following intra-articular injection, leading to a diagnosis of a hyaluronic acid embolus. Management involves injecting hyaluronidase into the lesion, while incorrect options relate to other vascular and thrombotic disorders. The last case presents a smooth pink papule on an elderly female’s forearm, diagnosed as an acquired elastotic hemangioma, highlighting its histological characteristics. Each case emphasizes the importance of accurate diagnosis and management approaches.