Please login or create an account. If you do not have access to this content, you will be shown a 30 second preview and licensing options.

  • Presentation

Alopecia in Cancer Patients and Survivors

Description

The presentation focuses on the impact of alopecia in cancer patients and survivors, highlighting that nearly half of diagnosed patients experience significant hair loss, which is often deemed the most traumatic side effect of cancer treatment. Alopecia affects quality of life, with some patients reportedly refusing chemotherapy due to fear of hair loss. The talk discusses the mechanisms behind chemotherapy-induced hair loss and reviews the efficacy of scalp cooling devices, which can help retain hair during treatment, with over 60% of users retaining significant hair coverage. However, these devices come with discomfort and potential side effects such as frostbite. Additionally, studies show that a considerable percentage of women undergoing chemotherapy do not fully regrow their hair, leading to distress and altered appearances. Various treatment options like low-dose minoxidil and PRP therapy are explored as potential remedies for post-chemotherapy alopecia. Evidence suggests a combination of interventions could enhance outcomes for patients, emphasizing the need for better awareness and involvement of dermatologists in the care of cancer survivors to address the psychological and aesthetic effects of hair loss.

View more

Conclusions

  • Cancer-related alopecia significantly impacts psychological well-being and treatment decisions for patients.
  • Advanced therapies have increased the number of cancer survivors, highlighting the importance of psychological support.
  • Scalp cooling is effective in preserving hair during chemotherapy, with over 60% of patients retaining significant hair.
  • Patients who use scalp cooling report improved quality of life compared to those who do not.
  • Significant rates of persistent alopecia are observed in patients post-chemotherapy, affecting up to 50% of breast cancer survivors.
  • Combination therapies, such as low-dose minoxidil or PRP, demonstrate potential benefits for managing cancer-related alopecia.
  • A multidisciplinary approach involving dermatology and oncology is crucial for optimal patient care after cancer treatment.
  • Panigrahi and Ambs, Trends Cancer 2021
  • Gallicchio et al, J Natl Cancer Inst 2022
  • Tonorezos et al, J Natl Cancer Inst 2024
  • American Association for Cancer Research 2024
  • Carelle et al, Cancer 2002
  • Shapiro, NEJM 2018
  • Luo et al, Supportive Care Cancer 2023
  • Freites-Martinez et al, J Am Acad Dermatol 2019
  • Paus et al, Lancet Oncology 2013
  • Kanti et al, Br J Dermatol 2014
  • Rugo et al; Nangia et al, JAMA 2017
  • Smetanay et al, Br Cancer Res Treat 2019
  • Hillman et al, Br J Dermatol 2012
  • Choi et al, JAAD 2013
  • Fonia et al, JAAD 2016
  • Kuo et al, ASCO Annual Meeting 2022
  • Kang et al, Supportive Care in Cancer 2020
  • Lacouture et al, San Antonio Breast Cancer Symp 2018
  • Kearney et al, AAD Annual Meeting 2025