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- Presentation
A.S.A.P. - The First Algorithm to Treat Keloids and Hypertrophic Scars: Tips and Tricks to Avoid Side-Effects in Higher Phototypes
Description
In this lecture, the presenter discusses the A.S.A.P. algorithm developed for treating keloids and hypertrophic scars, emphasizing the pain associated with injections due to the hardness of keloids. Key strategies involve softening scars with silicone or hydrocolloids before handling injections, primarily using steroids. While intralesional steroids remain a first-line treatment, their efficacy can lead to significant atrophy. The lecture delves into various treatments, including the use of Bleomycin and 5-Fluorouracil (5FU), noting their mechanisms and results, showing positive outcomes in managing keloids despite some side effects like pigmentation changes and ulceration. The presenter shares personal experiences with these treatments and highlights the importance of combining therapies for better results. Verapamil's potential as a new treatment is also discussed due to its safety and effectiveness. The concluding advice emphasizes proper techniques for injecting these treatments, urging caution to minimize complications.
View moreConclusions
- Combination treatments yield the best results for keloids and hypertrophic scars.
- Softening the scar with silicone or hydrocolloid tape before injections reduces pain during treatment.
- Intralesional steroid injections remain the first line treatment for keloids but have a high recurrence rate without additional therapies.
- Bleomycin shows promise as a low-cost, effective treatment for keloids when used in combination with surgical techniques.
- Ongoing research is needed to better understand and optimize treatments involving botulinum toxin and verapamil for keloid management.
- Surg Cosmet Dermatol. 2022;14:e20220100.
- Fathia M. Khattab, MD | Hagar Bessar, MD | Elsayed M. Khater, MD. Keloid therapy: A neoteric comparative study. DOI: 10.1111/jocd.15247.
- Hamideh Moravej, Ali Forghanian, Sahar Dadkhahfar, Nikoo Mozafari. Intralesional bleomycin versus intralesional triamcinolone in the treatment of keloids and hypertrophic scars. DOI: 10.1111/dth.15730.
- Doaa A. E. Abou-Taleb, Dalia M. Badary. Intralesional verapamil in the treatment of keloids: A clinical, histopathological, and immunohistochemical study. DOI: 10.1111/jocd.13476.
- 5-fluorouracil (5-FU): Lee DA, Shapourifar-Tehrani S, Kitada S. The effect of 5-fluorouracil and cytarabine on human fibroblasts. Invest Ophthalmol Vis Sci. 1990;31(9):1848-55.